解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::To compare the structures of natural and re-established populations of Ascaris in humans, universal (mass) chemotherapy was carried out at the beginning and the end of the study year using pyrantel pamoate. Worms expelled within 48 h of treatment were collected, their sex determined, and measurements made of length, w...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182002001737
更新日期:2002-06-01 00:00:00
abstract::Described in the present study is a major component of the cell wall of 2 of the most pathogenic parasites of molluscs, Perkinsus atlanticus and P. marinus. The component is a high molecular weight protein (233 kDa), which we have named PWP-1 (for Perkinsus wall protein-1). Western blots, using a polyclonal serum gene...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182002001415
更新日期:2002-05-01 00:00:00
abstract::The outcome of a parasite infection is the result of the interaction between the host and the parasite. In the system we studied, there are 3 critical stages for the outcome of infection of the (intermediate) host, the copepod Macrocyclops albidus, with the cestode Schistocephalus solidus. During the establishment pha...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001001275
更新日期:2002-04-01 00:00:00
abstract::Cryptosporidia are important protozoan parasites of vertebrates, and a number of species and genotypes, with different host ranges, have been described. In this study a protocol was established for the detection and the genetic characterization of Cryptosporidium spp. isolated from various types of surface waters (riv...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001001317
更新日期:2002-04-01 00:00:00
abstract::Trypanosoma evansi and Trypanosoma vivax are the most extensively distributed trypanosomes responsible for diseases in livestock. Western blot and indirect immunofluorescence assays revealed a high immunological cross-reaction between these two parasites. An antigen with an apparent molecular mass of 64 kDa (p64), whi...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001001214
更新日期:2002-03-01 00:00:00
abstract::Engorged Ixodes ricinus nymphs collected from sheep resident in an upland UK field site were significantly lighter than nymphs that engorged on previously tick-naïve sheep, indicating that site-resident sheep continually exposed to ticks acquired anti-tick resistance. The weights of engorged nymphs that fed on natural...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001001081
更新日期:2002-02-01 00:00:00
abstract::Most of our knowledge about the process of penetration of skin, by cercariae of Schistosoma mansoni, has been gained from studies carried out in vivo with laboratory animals. Human skin is significantly different from that of other animals but there are obvious practical difficulties in directly studying attachment an...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200100885x
更新日期:2002-01-01 00:00:00
abstract::Most, if not all, organisms face attack by natural enemies and will be selected to evolve some form of defence. Resistance may have costs as well as its obvious benefits. These costs may be associated with actual defence or with the maintenance of the defensive machinery irrespective of whether a challenge occurs. In ...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182002001750
更新日期:2002-01-01 00:00:00
abstract::The Baltic Sea is characterized by organisms that can tolerate brackish water. Because of the Sea's history during glacial times, its flora and fauna (and also their parasites) can be traced to marine, freshwater and genuine brackish elements beside glacial relics. Snails, planktonic copepods, benthic amphipods and is...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182002001567
更新日期:2002-01-01 00:00:00
abstract::A polymorphic set of 14 kDa excretory-secretory (E-S) antigen-encoding cDNAs, with similarity to a previously characterized 15 kDa E-S antigen of Haemonchus contortus, was cloned from Cooperia punctata. Five cDNAs encoding predicted proteins of 70-80% identity were sequenced. Genomic analyses of individuals proved the...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008770
更新日期:2001-12-01 00:00:00
abstract::A deterministic mathematical model which predicts the probability of developing a new drug-resistant parasite population within the human host is reported. The model incorporates the host's specific antibody response to PfEMP1, and also investigates the influence of chemotherapy on the probability of developing a viab...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008824
更新日期:2001-12-01 00:00:00
abstract::Voltage-gated calcium (Ca2+) channels contribute to impulse propagation in excitable cells and also regulate intracellular levels of Ca2+. High voltage-activated (HVA) Ca2+ channels are heteromultimeric membrane proteins. The pore-forming, voltage-sensing subunit is the alpha1 subunit. We have cloned 3 HVA Ca2+ channe...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008691
更新日期:2001-11-01 00:00:00
abstract::A 186 bp Echinococcus granulosus-specific repetitive element, TREg, was used to assess genetic variation between strains. In G7 genotype (pig strain) it has the characteristics of a satellite DNA element with a copy number of 23000 per haploid genome. Analysis, by sequencing of TREg monomers, showed a great degree of ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008575
更新日期:2001-10-01 00:00:00
abstract::Pasteuria penetrans is a Gram-positive endospore-producing bacterium that is a parasite of root-knot nematodes. Attachment of endospores to the cuticle of the nematode is the first stage in the infection process. Western blot analysis with monoclonal and polyclonal antibodies that recognize the 30 kDa heparin-binding ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008411
更新日期:2001-09-01 00:00:00
abstract::Ocular, peroral, intraperitoneal, intramuscular, and subcutaneous inoculation of severe combined immunodeficient (SCID) mice with spores of the human isolate (CDC: V404) of Brachiola algerae (syn. Nosema algerae) (Phylum Microspora) revealed that the microsporidium develops in viscera of the immunodeficient mouse host...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008228
更新日期:2001-08-01 00:00:00
abstract::Interferon-gamma (IFN-gamma) has a crucial role for host defence against parasite infection. It is not clear, however, how IFN-gamma affects the parasite-infected host cells. The effect of IFN-gamma on Neospora caninum-infected cells was investigated in murine fibroblasts and canine kidney cells in vitro. In the prese...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008095
更新日期:2001-07-01 00:00:00
abstract::Stability of trichostrogylid populations indicates that some form of density-dependent regulation occurs which could act through fecundity. We present evidence for intraspecific density-dependent effects in 1 of 2, dominant, abomasal nematodes species (Ostertagia gruehneri) of Svalbard reindeer (Rangifer tarandus plat...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001007818
更新日期:2001-06-01 00:00:00
abstract::The statistical aggregation of parasites among hosts is often described empirically by the negative binomial (Poisson-gamma) distribution. Alternatively, the Poisson-lognormal model can be used. This has the advantage that it can be fitted as a generalized linear mixed model, thereby quantifying the sources of aggrega...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001007740
更新日期:2001-05-01 00:00:00
abstract::The community structure of monogeneans on the gills of a catfish Pimelodus albicans, in the Río de la Plata, was studied and compared with previous findings on P. maulatus. Six Monogenea species belonging to 3 genera were found: Demidospermus majusculus Kritsky & Gutiérrez, 1998; Demidospermus armostus Kritsky & Gutié...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200100748x
更新日期:2001-04-01 00:00:00
abstract::Immunological and structural changes in the thymus and pronephros of Cyprinus carpio infected with the blood fluke, Sanguinicola inermis for 30 days, and exposed to 0.5 mg NH4+/1 for 48 and 168 h were investigated. Ultrastructural observations revealed cell disruption and highly vacuolated cytoplasm in the thymus. Of ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001007260
更新日期:2001-03-01 00:00:00
abstract::If the deleterious effects of non-specific parasites are greater on vulnerable host species than on reservoir host species then exclusion of the vulnerable host through apparent competition is more likely. Evidence suggests that such a mechanism occurs in interactions between the ring-necked pheasant (Phasianus colchi...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001007247
更新日期:2001-02-01 00:00:00
abstract::Infection with the endosymbiotic bacteria Wolbachia is widespread in filarial nematodes. Previous studies have suggested concordance between the phylogeny of Wolbachia with that of their nematode hosts. However, there is only one published molecular phylogenetic study of filarial species, based on the 5S rRNA gene spa...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000007149
更新日期:2001-01-01 00:00:00
abstract::Toxoplasma gondii has a unique enzyme, a NTPase, which has a wide specificity toward NTP. In the present study, we produced a monoclonal antibody (IgG1, 6C6) against the enzyme which could recognize NTPase isozymes among several strains of T. gondii. Three avirulent strains of T. gondii, ME49, Beverley and Nakayama, w...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000007101
更新日期:2001-01-01 00:00:00
abstract::Freshwater snails of the Bulinus forskalii group are one of four Bulinus species complexes responsible for the transmission of schistosomes in Africa and adjacent regions. The species status of these conchologically variable and widely distributed planorbids remains unclear, and parasite compatibility varies considera...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182001008381
更新日期:2001-01-01 00:00:00
abstract::In parallel with massive research efforts in human schistosomiasis over the past 30 years, persistent efforts have been made to understand the basis for compatibility and incompatibility in molluscan schistosomiasis. Snail plasma contains molecules that are toxic to trematodes, but these seem to kill only species that...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182001008137
更新日期:2001-01-01 00:00:00
abstract::Multiple parasitic infections have become increasingly recognized as a result of improvements in laboratory diagnosis and a growing population of immunocompromised individuals. This review examines the principles of chemotherapy in groupings of multiple infections which are of particular clinical significance. ...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182000017674
更新日期:2001-01-01 00:00:00
abstract::An endemic transmission cycle of Babesia microti was discovered in Colorado in the foothills of the Rocky Mountains. B. microti were found by PCR in 4 of 25 Ixodes spinipalpis tick pools tested (a 3.2 % minimum infection rate) and in 87% (13 of 15) of Microtus ochrogaster (the prairie vole) spleen and blood samples. U...
journal_title:Parasitology
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract::Endosymbiotic bacteria of the genus Wolbachia infect a number of invertebrate species in which they induce various alterations in host reproduction, mainly cytoplasmic incompatibility (CI). In contrast to most other maternally transmitted parasites, manipulation of host reproduction makes the spread of Wolbachia possi...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099006599
更新日期:2000-11-01 00:00:00
abstract::The sex ratio of adult worms has been observed biased towards males in Schistosoma mansoni under natural conditions. The origin of this bias is unknown. This paper determines whether males are more infective than females under controlled experimental bisexual conditions, and hence if the sex ratio is male-biased as a ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099006393
更新日期:2000-10-01 00:00:00
abstract::Eggs of Neoheterocotyle rhinobatidis, Troglocephalus rhinobatidis and Merizocotyle icopae (Monogenea: Monocotylidae) from the shovelnose ray Rhinobatos typus (Rhinobatidae) have a distinct hatching pattern linked to light periodicity. Larvae of these 3 monogenean species emerge only during daylight when exposed to nat...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118209900637x
更新日期:2000-09-01 00:00:00
abstract::This study describes morphological changes during capsule formation of Trichinella spiralis with emphasis on nuclei within the capsule. The nuclei of the pre-existing muscle cell may become hypertrophied or degrade soon after the entrance of newborn larvae. Cytoplasm associated with these hypertrophied nuclei was baso...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099006198
更新日期:2000-08-01 00:00:00
abstract::To investigate the quantitative distribution of Plasmodiumfalciparum gametocytes into the vector bloodmeal, Anopheles arabiensis mosquitoes were fed on 3 volunteers naturally infected with gametocytes. The content of each mosquito midgut was smeared on a microscope slide and Giemsa stained. The distribution of gametoc...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099006277
更新日期:2000-08-01 00:00:00
abstract::Members of the phylum Microspora are a group of unusual, obligate intracellular eukaryotic parasites that infect a wide range of hosts. However, there are a limited number of microsporidial infections reported in avian hosts, and no parasite species has been defined as an avian pathogen. A microsporidian organism was ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099005995
更新日期:2000-07-01 00:00:00
abstract::Schistosomiasis is a health problem in Brazil and the role of rodents in maintaining the schistosome life-cycle requires further clarification. The influence of Schistosoma mansoni on a population of Nectomys squamipes was studied by capture-recapture (1st phase, from June 1991 to November 1995) and removal (2nd phase...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099005892
更新日期:2000-06-01 00:00:00
abstract::Schistosoma mansoni depends for its survival on glycolysis. Two glycolytic enzymes, glyceraldehyde-3P-dehydrogenase and triose-phosphate dehydrogenase, found in both the adult and schistosomular tegument, have been reported to confer partial protection against cercarial infection. This paper describes the immunogenic ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099005648
更新日期:2000-05-01 00:00:00
abstract::Nitric oxide (NO) produced by cytokine-activated macrophages is reported to be cytotoxic against the helminth Schistosoma mansoni, although this is a controversial issue. Previous work in our laboratory identified a fraction of S. mansoni soluble adult worm antigenic preparation (SWAP), named PIII, able to elicit sign...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099005636
更新日期:2000-04-01 00:00:00
abstract::Existing models of the basic case reproduction number (R0) for vector-borne diseases assume (i) that the distribution of vectors over the susceptible host species is homogeneous and (ii) that the biting preference for the susceptible host species rather than other potential hosts is a constant. Empirical evidence cont...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099005442
更新日期:2000-03-01 00:00:00
abstract::Solid experimental evidence indicates that EBA-175 is used as a ligand by the Plasmodium falciparum merozoite to bind to human RBC, via different binding processing fragments. Using synthetic peptides and specific receptor-ligand interaction methodology, we have identified 6 high-activity binding sequences from the EB...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118209900551x
更新日期:2000-03-01 00:00:00
abstract::The effect of the parasitic swimbladder nematode, Anguillicola crassus, on the physiological status of wild European eels (Anguilla anguilla) was investigated during an 18 month survey (February 1995 until September 1996), and compared with that of wild uninfected eels collected over the same time-period. Despite the ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099005314
更新日期:2000-02-01 00:00:00
abstract::Infections with Haemonchus contortus are a major constraint on ruminant health world-wide. Young lambs are very sensitive to Haemonchus infection. Older lambs and sheep acquire immunity after a continuous or seasonal exposure to the parasite. The mechanisms underlying immunity are still not completely understood. Anti...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s003118209900579x
更新日期:2000-01-01 00:00:00